Einstein Experts for Media

Microbiology

William R. Jacobs Jr., Ph.D.

William R. Jacobs Jr., Ph.D.

Professor, Microbiology & Immunology, Einstein

Professor, Genetics, Einstein

Leo and Julia Forchheimer Chair in Microbiology & Immunology, Einstein

Investigator, Howard Hughes Medical Institute (HHMI)

Infectious diseasesTuberculosis (TB)Vaccines

Molecular genetics

Dr. Jacobs is pioneering the use of molecular genetics to control tuberculosis (TB), which kills nearly two million people a year. His research is identifying the genes that make Mycobacterium  tuberculosis (MTB) - the bacteria that causes TB -  virulent, identifying new drug targets and engineering weakened strains that can be used as live vaccines. Dr. Jacobs was the first scientist to introduce foreign DNA into MTB, a technique now regularly used by TB investigators around the world. read more...

 

Steven A. Porcelli, M.D.

Steven A. Porcelli, M.D.

Professor and Chair, Microbiology & Immunology

Professor, Medicine (Rheumatology)

Murray and Evelyne Weinstock Chair in Microbiology & Immunology

Microbiology & ImmunologyT-cell immunityTuberculosis (TB)

Dr. Porcelli studies the control of acquired immunity – the type that develops when our bodies generate specific responses involving antibodies or T cells following exposure to vaccines or infection by disease-causing microbes.  In particular, he investigates how T cells – which supervise both defense against microbes and immune tolerance – control the acquired immune response. read more...

 

Kartik Chandran, Ph.D.

Kartik Chandran, Ph.D.

Professor, Microbiology & Immunology

Harold and Muriel Block Faculty Scholar in Virology

COVID-19, Ebola, and emerging virusesAntibody-based therapiesAnti-viral therapeuticsVirus-host interactions

A recognized expert on emerging viruses, Dr. Chandran studies how viruses infect cells, and his research seeks to translate this knowledge into new antibody-based therapies. In 2020, Dr. Chandran helped lead Einstein’s research on COVID-19: Within weeks of the global outbreak, his laboratory created a “surrogate” coronavirus that allows scientists at Einstein and elsewhere to more safely study the virus. He also helped develop an antibody test for SARS-CoV-2 that is used clinically at Montefiore Health System and by researchers leading a convalescent plasma clinical trial. read more...

 

Harris Goldstein, M.D.

Harris Goldstein, M.D.

Professor, Department of Pediatrics (Pediatric Allergy & Immunology)

Professor, Department of Microbiology & Immunology

Associate Dean for Scientific Resources

Charles Michael Chair in Autoimmune Diseases

Director, Einstein-Rockefeller-CUNY Center for AIDS Research

HIV pathogenesis and HIV cure The immune system's antiviral activityEngineering molecules to attack virusesCAR-T cell structure and function Biologics against cancer and viruses

Dr. Goldstein’s NIH-funded research centers on developing agents to amplify the capacity of the immune system to control HIV infection and achieve a functional cure for the disease. In seeking to “weaponize” the immune system to cure HIV, his lab uses molecular, cellular, and biochemical approaches, including CAR-T cells and the novel treatment strategy developed by Dr. Almo at Einstein for selective T cell amplification called synTac (synthetic T-cell activation).  read more...