Drug that Boosts Brain's Cleansing System Improved Symptoms in Alzheimer's Mouse Model

Ana Maria Cuervo, M.D., Ph.D. and Evripidis Gavathiotis, Ph.D., developed an experimental drug that reinvigorates a cellular cleaning mechanism and reversed key symptoms of Alzheimer's disease in mice. Dr. Cuervo is professor of developmental and molecular biology, co-director of the Institute for Aging Research, and holds the Robert and Renée Belfer Chair for the Study of Neurodegenerative Diseases at Einstein. Dr. Gavathiotis is professor of biochemistry and of medicine.

The Scientist interviews Nir Barzilai, M.D., and Evris Gavathiotis, Ph.D., about their success in pursuing private funding in the face of federal funding cuts. Drs. Barzilai and Gavathiotis share how they identified and pursued alternative funding sources and how it has helped advance their research.  Dr. Barzilai is the Ingeborg and Ira Leon Rennert Chair of Aging Research and director of the Institute for Aging Research at Einstein and attending physician at Montefiore Medical Center. Dr. Gavathiotis is assistant professor of biochemistry and of medicine.